Ki Summary

Reaction Details

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Target

Protein kinase C delta type

Ligand

BDBM50080322

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_160928 (CHEMBL767167)

25±n/a nM

Citation

Wang, S; Liu, M; Lewin, NE; Lorenzo, PS; Bhattacharrya, D; Qiao, L; Kozikowski, AP; Blumberg, PM Probing the binding of indolactam-V to protein kinase C through site-directed mutagenesis and computational docking simulations. J Med Chem42:3436-46 (1999) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Protein kinase C delta type

Name:

Protein kinase C delta type

Synonyms:

Type:

PROTEIN

Mol. Mass.:

77554.99

Organism:

Mus musculus

Description:

ChEMBL_1351519

Residue:

674

Sequence:

MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFD
AHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQY
FLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSR
KLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGK
VLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDH
LFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLD
RDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEML
IGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPF
FKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHG
FSFVNPKFEQFLDI

BDBM50080322

n/a

Name

BDBM50080322

Synonyms:

Acetic acid (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9-acetoxy-4a,7b-dihydroxy-3-hydroxymethyl-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl ester | CHEMBL116437

Type

Small organic molecule

Emp. Form.

C24H32O8

Mol. Mass.

448.5061

SMILES

C[C@@H]1[C@@H](OC(C)=O)[C@]2(OC(C)=O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C |t:14,22|

Structure