| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50080805 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_61011 (CHEMBL675016) |
|---|
| Ki | 31±n/a nM |
|---|
| Citation |  Kesten, SR; Heffner, TG; Johnson, SJ; Pugsley, TA; Wright, JL; Wise, LD Design, synthesis, and evaluation of chromen-2-ones as potent and selective human dopamine D4 antagonists. J Med Chem42:3718-25 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50080805 |
|---|
| n/a |
|---|
| Name | BDBM50080805 |
|---|
| Synonyms: | 7-[(3-Phenylamino-propylamino)-methyl]-chromen-2-one | CHEMBL122427 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20N2O2 |
|---|
| Mol. Mass. | 308.3743 |
|---|
| SMILES | O=c1ccc2ccc(CNCCCNc3ccccc3)cc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
