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TargetThrombin and coagulation factor X
LigandBDBM50081157
Substrate/Competitorn/a
Meas. Tech.ChEBML_208905
Ki 1±n/a nM
Citation Minami NKReiner JESemple JE Asymmetric synthesis of novel quaternary alpha-hydroxy-delta-lactam dipeptide surrogates. Bioorg Med Chem Lett 9:2625-8 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Thrombin and coagulation factor X
Name:Thrombin and coagulation factor X
Synonyms:Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin | Prothrombin precursor | Thrombin heavy chain | Thrombin light chain
Type:Protein
Mol. Mass.:70029.57
Organism:Homo sapiens (Human)
Description:P00734
Residue:622
Sequence:
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
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  Blast E-value cutoff:
BDBM50081157
n/a
NameBDBM50081157
Synonyms:(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-2-oxo-3-phenylmethanesulfonylamino-piperidine-3-carboxylic acid ethyl ester | CHEMBL329865
TypeSmall organic molecule
Emp. Form.C23H34N6O7S
Mol. Mass.538.617
SMILESCCOC(=O)[C@@]1(CCCN(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)C1=O)NS(=O)(=O)Cc1ccccc1
Structure
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