| Reaction Details |
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 | Report a problem with these data |
| Target | rRNA adenine N-6-methyltransferase |
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| Ligand | BDBM50081299 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_67531 (CHEMBL679968) |
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| Ki | 3000±n/a nM |
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| Citation |  Hajduk, PJ; Dinges, J; Schkeryantz, JM; Janowick, D; Kaminski, M; Tufano, M; Augeri, DJ; Petros, A; Nienaber, V; Zhong, P; Hammond, R; Coen, M; Beutel, B; Katz, L; Fesik, SW Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis. J Med Chem42:3852-9 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| rRNA adenine N-6-methyltransferase |
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| Name: | rRNA adenine N-6-methyltransferase |
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| Synonyms: | ERM_STREE | ErmAM | Macrolide-lincosamide-streptogramin B resistance protein | erm |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28804.82 |
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| Organism: | Streptococcus pneumoniae |
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| Description: | ChEMBL_67532 |
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| Residue: | 245 |
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| Sequence: | MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELD
SHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIPYHLSTQIIKKVVFESHAS
DIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTT
DVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLL
FNGRK
|
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|
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| BDBM50081299 |
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| n/a |
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| Name | BDBM50081299 |
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| Synonyms: | CHEMBL125249 | N-(5-Fluoro-indan-2-yl)-6-piperidin-1-yl-[1,3,5]triazine-2,4-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21FN6 |
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| Mol. Mass. | 328.3872 |
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| SMILES | Nc1nc(NC2Cc3ccc(F)cc3C2)nc(n1)N1CCCCC1 |
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| Structure | 
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