| Reaction Details |
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 | Report a problem with these data |
| Target | Bile salt-activated lipase |
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| Ligand | BDBM50081696 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48915 (CHEMBL660745) |
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| Ki | 40±n/a nM |
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| Citation |  Deck, LM; Baca, ML; Salas, SL; Hunsaker, LA; Vander Jagt, DL 3-Alkyl-6-chloro-2-pyrones: selective inhibitors of pancreatic cholesterol esterase. J Med Chem42:4250-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Bile salt-activated lipase |
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| Name: | Bile salt-activated lipase |
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| Synonyms: | BAL | CEL | CEL_HUMAN | Cholesterol esterase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 79308.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_512655 |
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| Residue: | 753 |
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| Sequence: | MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTK
ALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPV
MIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPG
NYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQS
GVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYP
MLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVT
EEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA
LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV
SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLR
YWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSG
APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP
PTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDS
GAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF
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| BDBM50081696 |
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| n/a |
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| Name | BDBM50081696 |
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| Synonyms: | 6-Chloro-3-cyclopentyl-pyran-2-one | CHEMBL133091 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H11ClO2 |
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| Mol. Mass. | 198.646 |
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| SMILES | Clc1ccc(C2CCCC2)c(=O)o1 |
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| Structure | 
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