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TargetGag-Pol polyprotein [489-587]
LigandBDBM50082397
Substrate/Competitorn/a
Meas. Tech.ChEBML_79472
Ki 0.130000±n/a nM
Citation Patel, MRodgers, JDMcHugh, RJJohnson, BLCordova, BCKlabe, RMBacheler, LTErickson-Viitanen, SKo, SS Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents. Bioorg Med Chem Lett9:3217-20 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50082397
n/a
NameBDBM50082397
Synonyms:(4R,5S,6S,7R)-1-(3-Amino-benzyl)-4,7-dibenzyl-5,6-dihydroxy-3-(3-thiophen-3-yl-1H-indazol-5-ylmethyl)-[1,3]diazepan-2-one | CHEMBL323043
TypeSmall organic molecule
Emp. Form.C38H37N5O3S
Mol. Mass.643.797
SMILESNc1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3ccc4[nH]nc(-c5ccsc5)c4c3)C2=O)c1
Structure
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