| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50082625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201431 (CHEMBL809834) |
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| Ki | 0.96±n/a nM |
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| Citation |  Carroll, FI; Bai, X; Dehghani, A; Mascarella, SW; Williams, W; Bowen, WD Asymmetric synthesis of 9-alkyl-2-benzyl-6,7-benzomorphans: characterization as novel sigma receptor ligands. J Med Chem42:4621-9 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50082625 |
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| n/a |
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| Name | BDBM50082625 |
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| Synonyms: | (2R,6R,11R)-3-Benzyl-11-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine | CHEMBL140618 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N |
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| Mol. Mass. | 277.4033 |
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| SMILES | C[C@H]1[C@H]2Cc3ccccc3[C@@H]1CCN2Cc1ccccc1 |TLB:14:13:1:9.3.4| |
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| Structure | 
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