| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50083113 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1676 (CHEMBL616666) |
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| EC50 | 2.8±n/a nM |
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| Citation |  Russell, MG; Matassa, VG; Pengilley, RR; van Niel, MB; Sohal, B; Watt, AP; Hitzel, L; Beer, MS; Stanton, JA; Broughton, HB; Castro, JL 3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists. J Med Chem42:4981-5001 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50083113 |
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| n/a |
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| Name | BDBM50083113 |
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| Synonyms: | CHEMBL147660 | N-{4-[(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-methyl]-phenyl}-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H37N7O |
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| Mol. Mass. | 499.6504 |
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| SMILES | CN(CC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)Cc1ccc(NC(C)=O)cc1 |
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| Structure | 
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