| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
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| Ligand | BDBM50085920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158455 (CHEMBL763259) |
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| IC50 | 320±n/a nM |
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| Citation |  Wang, Y; Wos, JA; Dirr, MJ; Soper, DL; deLong, MA; Mieling, GE; De, B; Amburgey, JS; Suchanek, EG; Taylor, CJ Design and synthesis of 13,14-dihydro prostaglandin F(1alpha) analogues as potent and selective ligands for the human FP receptor. J Med Chem43:945-52 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin F2-alpha receptor |
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| Name: | Prostaglandin F2-alpha receptor |
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| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40072.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43088 |
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| Residue: | 359 |
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| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
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| BDBM50085920 |
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| n/a |
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| Name | BDBM50085920 |
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| Synonyms: | 7-{3,5-Dihydroxy-2-[3-hydroxy-4-(3-trifluoromethyl-phenylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid | CHEMBL172250 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H33F3O5S |
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| Mol. Mass. | 478.565 |
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| SMILES | OC(CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CSc1cccc(c1)C(F)(F)F |
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| Structure | 
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