Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM50085970 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_3622 (CHEMBL618125) |
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Ki | 20±n/a nM |
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Citation | Glennon, RA; Lee, M; Rangisetty, JB; Dukat, M; Roth, BL; Savage, JE; McBride, A; Rauser, L; Hufeisen, S; Lee, DK 2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors. J Med Chem43:1011-8 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM50085970 |
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n/a |
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Name | BDBM50085970 |
Synonyms: | CHEMBL7318 | [2-(5-Methoxy-2-phenyl-1H-indol-3-yl)-ethyl]-dimethyl-amine | [2-(5-Methoxy-2-phenyl-1H-indol-3-yl)-ethyl]-dimethyl-amine (C2H2O4) | [2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethylamine, 5 |
Type | Small organic molecule |
Emp. Form. | C19H22N2O |
Mol. Mass. | 294.3908 |
SMILES | COc1ccc2[nH]c(c(CCN(C)C)c2c1)-c1ccccc1 |
Structure |
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