| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50086364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145264 |
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| Ki | 5±n/a nM |
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| Citation |  Allen, MP; Blake, JF; Bryce, DK; Haggan, ME; Liras, S; McLean, S; Segelstein, BE Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands. Bioorg Med Chem Lett10:523-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM50086364 |
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| n/a |
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| Name | BDBM50086364 |
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| Synonyms: | CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methylamino-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N2O2 |
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| Mol. Mass. | 312.4061 |
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| SMILES | CNC(c1cccc(O)c1)C(C)(C)C(=O)NCc1ccccc1 |
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| Structure | 
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