| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50086643 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_144283 |
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| IC50 | 3.9±n/a nM |
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| Citation |  Lundquist, JT; Büllesbach, EE; Dix, TA Synthesis of neurotensin(9-13) analogues exhibiting enhanced human neurotensin receptor binding affinities. Bioorg Med Chem Lett10:453-5 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46278.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453811 |
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| Residue: | 418 |
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| Sequence: | MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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| BDBM50086643 |
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| n/a |
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| Name | BDBM50086643 |
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| Synonyms: | (S)-2-{(2S,3S)-2-[(S)-2-({(S)-1-[(S)-5-(3-Amino-propylamino)-2-azido-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid | CHEMBL141872 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H55N9O7 |
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| Mol. Mass. | 701.8566 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNCCCN)N=[N+]=[N-])C(=O)N[C@@H](CC(C)C)C(O)=O |
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| Structure | 
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