| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM50086668 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_37545 (CHEMBL647627) |
|---|
| Ki | >1000±n/a nM |
|---|
| Citation |  Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A (1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents. Bioorg Med Chem Lett10:465-8 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 50486.84 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P18090 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
|
|
|
|---|
| BDBM50086668 |
|---|
| n/a |
|---|
| Name | BDBM50086668 |
|---|
| Synonyms: | 7-{2-Hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propoxy}-4H-benzo[1,4]thiazin-3-one | CHEMBL142948 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27N3O4S |
|---|
| Mol. Mass. | 429.532 |
|---|
| SMILES | COc1ccccc1N1CCN(CC(O)COc2ccc3NC(=O)CSc3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
