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TargetOxytocin receptor
LigandBDBM50087282
Substrate/Competitorn/a
Meas. Tech.ChEMBL_220998
Ki 170±n/a nM
Citation Bélec LSlaninova JLubell WD A study of the relationship between biological activity and prolyl amide isomer geometry in oxytocin using 5-tert-butylproline to augment the Cys(6)-Pro(7) amide cis-isomer population. J Med Chem 43:1448-55 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Oxytocin receptor
Name:Oxytocin receptor
Synonyms:OT-R | Oxytocin
Type:Enzyme Catalytic Domain
Mol. Mass.:42889.28
Organism:RAT
Description:Oxytocin OXTR RAT::P70536
Residue:388
Sequence:
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50087282
n/a
NameBDBM50087282
Synonyms:2N-(1-carbamoylmethylcarbamoyl-3-methylbutyl)-5-(tert-butyl)-1-[11-(sec-butyl)-14-(2-carbamoylethyl)-17-carbamoylmethyl-8-(4-hydroxybenzyl)-4,4-dimethyl-6,9,12,15,18-pentaoxo-2,3-dithia-7,10,13,16,19-pentaazacyclononadecanylcarbonyl]tetrahydro-1 | CHEMBL263355
TypeSmall organic molecule
Emp. Form.C48H75N11O12S2
Mol. Mass.1062.306
SMILESCC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CC(C)(C)SS[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1C(CCC1C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O
Structure
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