| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine deaminase |
|---|
| Ligand | BDBM50087317 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_7178 (CHEMBL620222) |
|---|
| Ki | 450±n/a nM |
|---|
| Citation |  Bookser, BC; Kasibhatla, SR; Appleman, JR; Erion, MD AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series. J Med Chem43:1495-507 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine deaminase |
|---|
| Name: | Adenosine deaminase |
|---|
| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40910.44 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 363 |
|---|
| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
|
|
|
|---|
| BDBM50087317 |
|---|
| n/a |
|---|
| Name | BDBM50087317 |
|---|
| Synonyms: | 3-Octyl-3,6,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol 0.25H2O | CHEMBL290949 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H24N4O |
|---|
| Mol. Mass. | 264.3666 |
|---|
| SMILES | CCCCCCCCn1cnc2C(O)CNC=Nc12 |c:16| |
|---|
| Structure | 
|
|---|
Search and Browse
