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TargetCoagulation factor X
LigandBDBM50079252
Substrate/Competitorn/a
Meas. Tech.ChEBML_48953
Ki 0.800000±n/a nM
Citation Pruitt JRPinto DJEstrella MJBostrom LLKnabb RMWong PCWright MRWexler RR Isoxazolines and isoxazoles as factor Xa inhibitors. Bioorg Med Chem Lett 10:685-9 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor X
Name:Coagulation factor X
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:53951.21
Organism:Oryctolagus cuniculus
Description:ChEMBL_1471174
Residue:490
Sequence:
MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEE
NCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQD
CEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRW
RRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCR
DGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEET
HEVEVVVKHNRFVKETYDFDIAVLRLKTPITFRRNVAPACLPQKDWAESTLMAQKTGIVS
GFGRTHEMGRLSTTLKMLEVPYVDRNSCKRSSSFTITQNMFCAGYDARPEDACQGDSGGP
HVTRFRDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIEKSMRARAVPVAEAAGTPGP
TQPTIKGSPS
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  Blast E-value cutoff:
BDBM50079252
n/a
NameBDBM50079252
Synonyms:3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide; TFA | CHEMBL328298 | CHEMBL350499
TypeSmall organic molecule
Emp. Form.C25H25N5O5S
Mol. Mass.507.562
SMILESCOCC1(CC(=NO1)c1cccc(c1)C(N)=N)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |c:5|
Structure
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