Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGag-Pol polyprotein [489-587]
LigandBDBM50088256
Substrate/Competitorn/a
Meas. Tech.ChEMBL_90557 (CHEMBL702247)
IC50 6000±n/a nM
Citation Molteni, VRhodes, DRubins, KHansen, MBushman, FDSiegel, JS A new class of HIV-1 integrase inhibitors: the 3,3,3', 3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6'-tetrol family. J Med Chem43:2031-9 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50088256
n/a
NameBDBM50088256
Synonyms:6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3-dihydro-1H-indene]-5,5'-dicarbaldehyde | CHEMBL417029
TypeSmall organic molecule
Emp. Form.C23H24O4
Mol. Mass.364.4343
SMILESCC1(C)CC2(CC(C)(C)c3cc(C=O)c(O)cc23)c2cc(O)c(C=O)cc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: