| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50088466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31844 (CHEMBL641521) |
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| Ki | 172±n/a nM |
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| Citation |  van Muijlwijk-Koezen, JE; Timmerman, H; van der Goot, H; Menge, WM; Frijtag Von Drabbe Künzel, J; de Groote, M; IJzerman, AP Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem43:2227-38 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50088466 |
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| n/a |
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| Name | BDBM50088466 |
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| Synonyms: | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline-6-carboxylic acid methyl ester | CHEMBL309755 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N3O2 |
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| Mol. Mass. | 319.3572 |
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| SMILES | COC(=O)C1=C2C=CC(C)C=C2c2nc(nn2C1)-c1ccccc1 |c:4,6,10| |
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| Structure | 
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