| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50088868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1733 |
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| Ki | 4.5±n/a nM |
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| Citation |  Meng, CQ; Rakhit, S; Lee, DK; Kamboj, R; McCallum, KL; Mazzocco, L; Dyne, K; Slassi, A 5-Thienyltryptamine derivatives as serotonin 5-HT1B/1D receptor agonists: potential treatments for migraine. Bioorg Med Chem Lett10:903-5 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50088868 |
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| n/a |
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| Name | BDBM50088868 |
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| Synonyms: | 3-[2-(2,5-Dihydro-pyrrol-1-yl)-ethyl]-5-thiophen-2-yl-1H-indole | CHEMBL173162 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2S |
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| Mol. Mass. | 294.414 |
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| SMILES | C(Cc1c[nH]c2ccc(cc12)-c1cccs1)N1CC=CC1 |c:21| |
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| Structure | 
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