| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
|---|
| Ligand | BDBM50088862 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1361 |
|---|
| Ki | 476.0±n/a nM |
|---|
| Citation |  Meng, CQ; Rakhit, S; Lee, DK; Kamboj, R; McCallum, KL; Mazzocco, L; Dyne, K; Slassi, A 5-Thienyltryptamine derivatives as serotonin 5-HT1B/1D receptor agonists: potential treatments for migraine. Bioorg Med Chem Lett10:903-5 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1B |
|---|
| Name: | 5-hydroxytryptamine receptor 1B |
|---|
| Synonyms: | 5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43579.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells |
|---|
| Residue: | 390 |
|---|
| Sequence: | MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
|
|
|
|---|
| BDBM50088862 |
|---|
| n/a |
|---|
| Name | BDBM50088862 |
|---|
| Synonyms: | 5-(5-Chloro-thiophen-2-yl)-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CHEMBL423610 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H19ClN2S |
|---|
| Mol. Mass. | 330.875 |
|---|
| SMILES | Clc1ccc(s1)-c1ccc2[nH]cc(CCN3CCCC3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
