| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein kinase CSK |
|---|
| Ligand | BDBM50088899 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_225999 |
|---|
| IC50 | >5000±n/a nM |
|---|
| Citation |  Missbach, M; Altmann, E; Widler, L; Susa, M; Buchdunger, E; Mett, H; Meyer, T; Green, J Substituted 5,7-diphenyl-pyrrolo[2,3d]pyrimidines: potent inhibitors of the tyrosine kinase c-Src. Bioorg Med Chem Lett10:945-9 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein kinase CSK |
|---|
| Name: | Tyrosine-protein kinase CSK |
|---|
| Synonyms: | C-SRC kinase | C-src tyrosine kinase | CSK | CSK_HUMAN | Protein-tyrosine kinase CYL | Tyrosine Kinase CSK |
|---|
| Type: | Tyrosine-protein kinase |
|---|
| Mol. Mass.: | 50707.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41240 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAAMRPSFLQLREQLEHIKTHELHL
|
|
|
|---|
| BDBM50088899 |
|---|
| n/a |
|---|
| Name | BDBM50088899 |
|---|
| Synonyms: | 2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)benzylamino)ethanol | 2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-benzylamino}-ethanol | CHEMBL424375 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23N5O2 |
|---|
| Mol. Mass. | 389.4503 |
|---|
| SMILES | COc1cccc(c1)-c1cn(-c2ccc(CNCCO)cc2)c2ncnc(N)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
