| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50089287 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39236 (CHEMBL655732) |
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| Ki | >1000000±n/a nM |
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| Comments | >0.000010 20220122 |
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| Citation |  Cristau, M; Devin, C; Oiry, C; Chaloin, O; Amblard, M; Bernad, N; Heitz, A; Fehrentz, JA; Martinez, J Synthesis and biological evaluation of bombesin constrained analogues. J Med Chem43:2356-61 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | GRPR_RAT | Gastrin-Releasing peptide | Gastrin-releasing peptide receptor | Grpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43227.55 |
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| Organism: | RAT |
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| Description: | Gastrin-Releasing peptide 0 RAT::P52500 |
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| Residue: | 384 |
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| Sequence: | MDPNNCSHLNLEVDPFLSCNNTFNQTLSPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMT
SFKSTNPSATFSLINGNICHEGYV
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| BDBM50089287 |
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| n/a |
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| Name | BDBM50089287 |
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| Synonyms: | Bombesin analogues | CHEMBL384242 |
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| Type | Small organic molecule |
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| Emp. Form. | C55H70N14O10 |
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| Mol. Mass. | 1087.2321 |
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| SMILES | CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)Cn1c2ccccc2c(=O)n(CCNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCC(N)=O)NC(=O)[C@H](N)Cc2ccccc2)c1=O)C(N)=O |
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| Structure | 
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