| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
|---|
| Ligand | BDBM50089291 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_39236 (CHEMBL655732) |
|---|
| Ki | 5.2±n/a nM |
|---|
| Citation |  Cristau, M; Devin, C; Oiry, C; Chaloin, O; Amblard, M; Bernad, N; Heitz, A; Fehrentz, JA; Martinez, J Synthesis and biological evaluation of bombesin constrained analogues. J Med Chem43:2356-61 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin-releasing peptide receptor |
|---|
| Name: | Gastrin-releasing peptide receptor |
|---|
| Synonyms: | GRPR_RAT | Gastrin-Releasing peptide | Gastrin-releasing peptide receptor | Grpr |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 43227.55 |
|---|
| Organism: | RAT |
|---|
| Description: | Gastrin-Releasing peptide 0 RAT::P52500 |
|---|
| Residue: | 384 |
|---|
| Sequence: | MDPNNCSHLNLEVDPFLSCNNTFNQTLSPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMT
SFKSTNPSATFSLINGNICHEGYV
|
|
|
|---|
| BDBM50089291 |
|---|
| n/a |
|---|
| Name | BDBM50089291 |
|---|
| Synonyms: | CHEMBL415021 | JMV 1813 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C49H66N12O10 |
|---|
| Mol. Mass. | 983.1227 |
|---|
| SMILES | COC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CN1CCCCC(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCC(N)=O)NC(=O)[C@H](N)Cc2ccccc2)C1=O |
|---|
| Structure | 
|
|---|
Search and Browse
