| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50090607 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48997 |
|---|
| Ki | >1200±n/a nM |
|---|
| Citation |  He, W; Hanney, B; Myers, MR; Spada, AP; Brown, K; Colussi, D; Chu, V Nonbenzamidine compounds as selective factor Xa inhibitors. Bioorg Med Chem Lett10:1737-9 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54726.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 488 |
|---|
| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
|
|
|
|---|
| BDBM50090607 |
|---|
| n/a |
|---|
| Name | BDBM50090607 |
|---|
| Synonyms: | 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-methyl-N-pyridin-4-yl-acetamide | CHEMBL45839 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H19ClN4O4S2 |
|---|
| Mol. Mass. | 478.972 |
|---|
| SMILES | CN(C(=O)CN1CCN(CC1=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1)c1ccncc1 |
|---|
| Structure | 
|
|---|
Search and Browse
