| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50090759 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58670 (CHEMBL670444) |
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| Ki | >1000±n/a nM |
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| Citation |  Hammarberg, E; Nordvall, G; Leideborg, R; Nylöf, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csöregh, I; Johansson, R Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor. J Med Chem43:2837-50 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50090759 |
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| n/a |
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| Name | BDBM50090759 |
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| Synonyms: | (R)-3-Dipropylamino-chroman-5-carboxylic acid isopropylamide | (S)-3-Dipropylamino-chroman-5-carboxylic acid isopropylamide | CHEMBL95688 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N2O2 |
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| Mol. Mass. | 318.4537 |
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| SMILES | CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1 |
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| Structure | 
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