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Target5-hydroxytryptamine receptor 2A
LigandBDBM50090764
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2665 (CHEMBL617913)
Ki>1000±n/a nM
Citation Hammarberg, ENordvall, GLeideborg, RNylöf, MHanson, SJohansson, LThorberg, SOTolf, BRJerning, ESvantesson, GTMohell, NAhlgren, CWestlind-Danielsson, ACsöregh, IJohansson, R Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor. J Med Chem43:2837-50 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52852.05
Organism:Rattus norvegicus (rat)
Description:Rat cortex membranes 5-HT2A receptors.
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50090764
n/a
NameBDBM50090764
Synonyms:(R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxylic acid amide | CHEMBL97268
TypeSmall organic molecule
Emp. Form.C16H24N2O2
Mol. Mass.276.374
SMILESCCCN(C(C)C)C1COc2cccc(C(N)=O)c2C1
Structure
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