| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50091137 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32017 (CHEMBL649053) |
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| Ki | 2.9±n/a nM |
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| Citation |  Colotta, V; Catarzi, D; Varano, F; Cecchi, L; Filacchioni, G; Martini, C; Trincavelli, L; Lucacchini, A Synthesis and structure-activity relationships of a new set of 2-arylpyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists. J Med Chem43:3118-24 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50091137 |
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| n/a |
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| Name | BDBM50091137 |
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| Synonyms: | 2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[3,4-c]quinolin-4-one | CHEMBL106740 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10ClN3O |
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| Mol. Mass. | 295.723 |
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| SMILES | Clc1ccc(cc1)-n1cc2c(n1)c(=O)[nH]c1ccccc21 |
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| Structure | 
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