| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50092050 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_60226 |
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| Ki | >1000±n/a nM |
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| Citation |  Zhao, H; Thurkauf, A; Braun, J; Brodbeck, R; Kieltyka, A Design, synthesis, and discovery of 3-piperazinyl-3,4-dihydro-2(1H)-quinolinone derivatives: a novel series of mixed dopamine D2/D4 receptor antagonists. Bioorg Med Chem Lett10:2119-22 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50092050 |
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| n/a |
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| Name | BDBM50092050 |
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| Synonyms: | 1,3-Diethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3-dihydro-indol-2-one | CHEMBL304777 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31N3O |
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| Mol. Mass. | 377.5224 |
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| SMILES | CCN1C(=O)C(CC)(N2CCN(Cc3ccc(C)cc3)CC2)c2ccccc12 |
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| Structure | 
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