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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Insulin receptor | ||
| Ligand | BDBM50092146 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_88875 (CHEMBL698212) | ||
| EC50 | 1500±n/a nM | ||
| Citation |  Liu, K; Xu, L; Szalkowski, D; Li, Z; Ding, V; Kwei, G; Huskey, S; Moller, DE; Heck, JV; Zhang, BB; Jones, AB Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor. J Med Chem43:3487-94 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Insulin receptor | |||
| Name: | Insulin receptor | ||
| Synonyms: | INSR | INSR protein | INSR_HUMAN | Insulin receptor (IR) | Insulin receptor beta subunit | ||
| Type: | Receptor Tyrosine Kinase | ||
| Mol. Mass.: | 156322.60 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P06213 | ||
| Residue: | 1382 | ||
| Sequence: |
| ||
| BDBM50092146 | |||
| n/a | |||
| Name | BDBM50092146 | ||
| Synonyms: | 2-Benzofuran-3-yl-3,6-dihydroxy-5-phenyl-[1,4]benzoquinone | CHEMBL116907 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H12O5 | ||
| Mol. Mass. | 332.3063 | ||
| SMILES | O=C1C(c2coc3ccccc23)C(=O)C(=O)C(C1=O)c1ccccc1 |(8.69,-8.66,;8.69,-7.12,;7.37,-6.35,;6.03,-7.12,;6.52,-8.59,;5.28,-9.5,;4.04,-8.62,;2.53,-8.97,;1.47,-7.82,;1.94,-6.32,;3.46,-5.98,;4.51,-7.12,;7.37,-4.81,;6.03,-4.04,;8.69,-4.04,;8.69,-2.5,;10.02,-4.81,;10.02,-6.35,;11.36,-7.12,;11.36,-4.04,;11.35,-2.52,;12.68,-1.75,;14.03,-2.53,;14.02,-4.07,;12.68,-4.83,)| | ||
| Structure | 
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