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TargetKappa-type opioid receptor
LigandBDBM50092519
Substrate/Competitorn/a
Meas. Tech.ChEMBL_145389
Ki 190±n/a nM
Citation Siener TCambareri AKuhl UEnglberger WHaurand MKögel BHolzgrabe U Synthesis and opioid receptor affinity of a series of 2, 4-diaryl-substituted 3,7-diazabicylononanones. J Med Chem 43:3746-51 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | kappa opioid receptor (KOR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42648.76
Organism:Homo sapiens (Human)
Description:P41145
Residue:380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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  Blast E-value cutoff:
BDBM50092519
n/a
NameBDBM50092519
Synonyms:3-{[(Methoxycarbonyl-quinolin-2-yl-methyl)-methyl-amino]-quinolin-2-yl-methyl}-1-methyl-4-oxo-piperidine-3-carboxylic acid methyl ester | CHEMBL369719
TypeSmall organic molecule
Emp. Form.C31H30N4O5
Mol. Mass.538.5937
SMILESCOC(=O)C12CN(C)CC(C(N(C)C1c1ccc3ccccc3n1)c1ccc3ccccc3n1)(C(=O)OC)C2=O |TLB:12:11:38:6.8.5,14:13:38:6.8.5,24:10:38:6.8.5|
Structure
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