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TargetDelta-type opioid receptor
LigandBDBM50084251
Substrate/Competitorn/a
Meas. Tech.ChEMBL_145312 (CHEMBL751918)
EC50 37±n/a nM
Citation Wei, ZYBrown, WTakasaki, BPlobeck, NDelorme, DZhou, FYang, HJones, PGawell, LGagnon, HSchmidt, RYue, SYWalpole, CPayza, KSt-Onge, SLabarre, MGodbout, CJakob, AButterworth, JKamassah, AMorin, PEProjean, DDucharme, JRoberts, E N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues. J Med Chem43:3895-905 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50084251
n/a
NameBDBM50084251
Synonyms:CHEMBL338980 | N,N-Diethyl-4-(phenyl-piperazin-1-yl-methyl)-benzamide
TypeSmall organic molecule
Emp. Form.C22H29N3O
Mol. Mass.351.4852
SMILESCCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccccc1
Structure
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