| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50084251 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145606 (CHEMBL749749) |
|---|
| IC50 | 8150±n/a nM |
|---|
| Citation |  Wei, ZY; Brown, W; Takasaki, B; Plobeck, N; Delorme, D; Zhou, F; Yang, H; Jones, P; Gawell, L; Gagnon, H; Schmidt, R; Yue, SY; Walpole, C; Payza, K; St-Onge, S; Labarre, M; Godbout, C; Jakob, A; Butterworth, J; Kamassah, A; Morin, PE; Projean, D; Ducharme, J; Roberts, E N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues. J Med Chem43:3895-905 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50084251 |
|---|
| n/a |
|---|
| Name | BDBM50084251 |
|---|
| Synonyms: | CHEMBL338980 | N,N-Diethyl-4-(phenyl-piperazin-1-yl-methyl)-benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H29N3O |
|---|
| Mol. Mass. | 351.4852 |
|---|
| SMILES | CCN(CC)C(=O)c1ccc(cc1)C(N1CCNCC1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
