| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50093301 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213033 (CHEMBL816971) |
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| IC50 | 2500±n/a nM |
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| Citation |  Dudley, DA; Bunker, AM; Chi, L; Cody, WL; Holland, DR; Ignasiak, DP; Janiczek-Dolphin, N; McClanahan, TB; Mertz, TE; Narasimhan, LS; Rapundalo, ST; Trautschold, JA; Van Huis, CA; Edmunds, JJ Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors. J Med Chem43:4063-70 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50093301 |
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| n/a |
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| Name | BDBM50093301 |
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| Synonyms: | 3-[4-(5-Dihexylamino-pentyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl]-benzamidine | CHEMBL133328 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H48N4O2 |
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| Mol. Mass. | 520.7491 |
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| SMILES | CCCCCCN(CCCCCC)CCCCCN1C(=O)C(Oc2ccccc12)c1cccc(c1)C(N)=N |
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| Structure | 
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