| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calpain small subunit 1 |
|---|
| Ligand | BDBM50093806 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_43687 |
|---|
| Ki | 11130±n/a nM |
|---|
| Citation |  Donkor, IO; Zheng, X; Miller, DD Synthesis and calpain inhibitory activity of alpha-ketoamides with 2,3-methanoleucine stereoisomers at the P2 position. Bioorg Med Chem Lett10:2497-500 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calpain small subunit 1 |
|---|
| Name: | Calpain small subunit 1 |
|---|
| Synonyms: | CANP small subunit | CAPN4 | CAPNS1 | CDPS | CPNS1_PIG | CSS1 | Calcium-activated neutral proteinase small subunit | Calcium-dependent protease small subunit | Calcium-dependent protease small subunit 1 | Calpain regulatory subunit |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28062.13 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_43862 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRIL
GGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMN
ILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFD
VDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRA
FKSLDKDGTGQIQVNIQEWLQLTMYS
|
|
|
|---|
| BDBM50093806 |
|---|
| n/a |
|---|
| Name | BDBM50093806 |
|---|
| Synonyms: | CHEMBL445563 | [(1S,2R)-1-((S)-1-Benzyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-2-isopropyl-cyclopropyl]-carbamic acid benzyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H37N3O5 |
|---|
| Mol. Mass. | 555.664 |
|---|
| SMILES | CC(C)[C@H]1C[C@@]1(NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
