| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50094634 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145391 (CHEMBL750081) |
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| Ki | 1058±n/a nM |
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| Citation |  Shinkai, H; Ito, T; Iida, T; Kitao, Y; Yamada, H; Uchida, I 4-Aminoquinolines: novel nociceptin antagonists with analgesic activity. J Med Chem43:4667-77 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM50094634 |
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| n/a |
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| Name | BDBM50094634 |
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| Synonyms: | CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-2-(4-ethyl-phenoxymethyl)-benzamide | N-(4-amino-2-methylquinolin-6-yl)-2-((4-ethylphenoxy)methyl)benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25N3O2 |
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| Mol. Mass. | 411.4956 |
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| SMILES | CCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 |
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| Structure | 
|
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