| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50095043 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_60046 |
|---|
| Ki | 17±n/a nM |
|---|
| Citation |  Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL 2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor. Bioorg Med Chem Lett10:2697-9 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 50647.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14416 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50095043 |
|---|
| n/a |
|---|
| Name | BDBM50095043 |
|---|
| Synonyms: | CHEMBL90911 | Ethyl-methyl-{2-[2-(3-trifluoromethyl-phenyl)-1H-indol-3-yl]-ethyl}-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21F3N2 |
|---|
| Mol. Mass. | 346.3893 |
|---|
| SMILES | CCN(C)CCc1c([nH]c2ccccc12)-c1cccc(c1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
