| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50069294 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212520 |
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| Ki | 33±n/a nM |
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| Citation |  Lee, K; Jung, WH; Kang, M; Lee, SH Noncovalent thrombin inhibitors incorporating an imidazolylethynyl P1. Bioorg Med Chem Lett10:2775-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50069294 |
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| n/a |
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| Name | BDBM50069294 |
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| Synonyms: | (S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopentyl-N-methyl-2-(naphthalene-2-sulfonylamino)-propionamide | (S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro-naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentylamide | 1N-cyclopentyl-1N-methyl-3-(4-Carbohydrazonamidephenyl)-2-(2-naphthylsulfonamido)-(2S)-propanamide | 1N-cyclopentyl-3-[4-amino(aminoimino)methylphenyl]-2-(2-naphthylsulfinamido)propanamide | Benzamidrazone analogue | CHEMBL7962 | N-methyl-N-cyclopentyl-3-(4-hydrazonoformamidephenyl)-2-[(2-naphthylsulfonyl)amino]propanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N5O3S |
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| Mol. Mass. | 493.621 |
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| SMILES | CN(C1CCCC1)C(=O)[C@H](Cc1ccc(cc1)C(N)=NN)NS(=O)(=O)c1ccc2ccccc2c1 |w:19.21| |
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| Structure | 
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