| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
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| Ligand | BDBM50096680 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48703 (CHEMBL659778) |
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| Ki | 4600±n/a nM |
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| Citation |  Wipf, P; Aslan, DC; Southwick, EC; Lazo, JS Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases. Bioorg Med Chem Lett11:313-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 2 |
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| Name: | M-phase inducer phosphatase 2 |
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| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 64985.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 580 |
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| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
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| BDBM50096680 |
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| n/a |
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| Name | BDBM50096680 |
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| Synonyms: | (E)-2-(2-Chloro-phenyl)-ethenesulfonic acid [4-(4-chloro-phenyl)-5-propyl-thiazol-2-yl]-amide | CHEMBL421227 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18Cl2N2O2S2 |
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| Mol. Mass. | 453.405 |
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| SMILES | CCCc1sc(NS(=O)(=O)\C=C\c2ccccc2Cl)nc1-c1ccc(Cl)cc1 |
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| Structure | 
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