| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50096820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_200365 |
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| Ki | 8.6±n/a nM |
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| Citation |  Zhou, C; Guo, L; Morriello, G; Pasternak, A; Pan, Y; Rohrer, SP; Birzin, ET; Huskey, SE; Jacks, T; Schleim, KD; Cheng, K; Schaeffer, JM; Patchett, AA; Yang, L Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists. Bioorg Med Chem Lett11:415-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50096820 |
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| n/a |
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| Name | BDBM50096820 |
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| Synonyms: | (S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-((S)-1-methoxycarbonyl-2-phenyl-ethylcarbamoyl)-piperidine-3-carbonyl]-amino}-butyrylamino)-hexanoic acid tert-butyl ester | CHEMBL132610 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H54N6O7 |
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| Mol. Mass. | 718.8821 |
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| SMILES | COC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCCC(C1)C(=O)NC([C@@H](C)c1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C |
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| Structure | 
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