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TargetCAAX prenyl protease 2
LigandBDBM50096860
Substrate/Competitorn/a
Meas. Tech.ChEMBL_194934 (CHEMBL879065)
IC50 7000±n/a nM
Citation Schlitzer, MWinter-Vann, ACasey, PJ Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1. Bioorg Med Chem Lett11:425-7 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
CAAX prenyl protease 2
Name:CAAX prenyl protease 2
Synonyms:CAAX prenyl protease 2 | FACE-2 | FACE2 | FACE2_HUMAN | Farnesylated proteins-converting enzyme 2 | Prenyl protein specific protease | Prenyl protein-specific endoprotease 2 | RCE1 | RCE1 homolog | RCE1A | RCE1B | hRCE1
Type:PROTEIN
Mol. Mass.:35839.94
Organism:Homo sapiens (Human)
Description:ChEMBL_194935
Residue:329
Sequence:
MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSEL
PRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPL
LLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFR
ACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVF
GAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQ
PLTDPKLYGSLPLCVLLERAGDSEAPLCS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50096860
n/a
NameBDBM50096860
Synonyms:(E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsulfamoyl)-phenylcarbamoyl]-ethyl}-acrylamide | CHEMBL423158
TypeSmall organic molecule
Emp. Form.C32H31N3O4S
Mol. Mass.553.671
SMILESCc1cccc(NS(=O)(=O)c2cccc(NC(=O)CCNC(=O)\C=C\c3ccc(cc3)-c3ccccc3)c2)c1C
Structure
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