| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM12751 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48951 (CHEMBL661664) |
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| Ki | 0.030000±n/a nM |
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| Citation |  Fevig, JM; Pinto, DJ; Han, Q; Quan, ML; Pruitt, JR; Jacobson, IC; Galemmo, RA; Wang, S; Orwat, MJ; Bostrom, LL; Knabb, RM; Wong, PC; Lam PYS, na; Wexler, RR Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core. Bioorg Med Chem Lett11:641-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | F10 | FA10_RABIT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53951.21 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_1471174 |
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| Residue: | 490 |
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| Sequence: | MANPLHLVLLGAALAGLLLSGSSVFISRRAANDVLARTRRANSFLEELKKGNLERECMEE
NCSYEEALEVFEDREKTNEFWNKYVDGDQCESNPCQNQGTCKDGLGMYTCSCVEGYEGQD
CEPVTRKLCSLDNGGCDQFCKEEENSVLCSCASGYTLGDNGKSCISTELFPCGKVTLGRW
RRSPATNSSEGPPEAPGPEQQDDGNLTATENPFNLLDSPEPPPEDDSSSLVRIVGGQDCR
DGECPWQALLVNEENEGFCGGTILSEYHVLTAAHCLHQAKRFKVRVGDRDTEHEEGNEET
HEVEVVVKHNRFVKETYDFDIAVLRLKTPITFRRNVAPACLPQKDWAESTLMAQKTGIVS
GFGRTHEMGRLSTTLKMLEVPYVDRNSCKRSSSFTITQNMFCAGYDARPEDACQGDSGGP
HVTRFRDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIEKSMRARAVPVAEAAGTPGP
TQPTIKGSPS
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| BDBM12751 |
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| n/a |
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| Name | BDBM12751 |
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| Synonyms: | 1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamoylphenyl)phenyl]-1H-pyrazole-5-carboxamide | CHEMBL152854 | CHEMBL37251 | SN-429 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N6O3S |
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| Mol. Mass. | 474.535 |
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| SMILES | Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1cccc(c1)C(N)=N |
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| Structure | 
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