Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target5-hydroxytryptamine receptor 2C
LigandBDBM35920
Substrate/Competitorn/a
Meas. Tech.ChEBML_2780
Ki 43±n/a nM
Citation Runyon, SPSavage, JETaroua, MRoth, BLGlennon, RAWestkaemper, RB Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene. Bioorg Med Chem Lett11:655-8 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2C
Name:5-hydroxytryptamine receptor 2C
Synonyms:5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2C) | 5HT2C_MOUSE | 5ht1c | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr1c | Htr2c | Serotonin 2c (5-HT2c) receptor
Type:Enzyme
Mol. Mass.:51948.16
Organism:Mus musculus (Mouse)
Description:P34968
Residue:459
Sequence:
MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGT
MQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYV
CSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHT
NERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM35920
n/a
NameBDBM35920
Synonyms:9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-9,10-dihydroanthracene | 9-aminomethyl-9,10-dihydroanthracene | C-(9,10-Dihydro-anthracen-9-yl)-methylamine | CHEMBL47482
TypeSmall organic molecule
Emp. Form.C15H15N
Mol. Mass.209.2863
SMILESNCC1c2ccccc2Cc2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: