| Reaction Details |
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 | Report a problem with these data |
| Target | Vascular cell adhesion protein 1 |
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| Ligand | BDBM50098517 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213817 (CHEMBL815900) |
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| IC50 | >1000±n/a nM |
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| Citation |  Stewart, AO; Bhatia, PA; McCarty, CM; Patel, MV; Staeger, MA; Arendsen, DL; Gunawardana, IW; Melcher, LM; Zhu, GD; Boyd, SA; Fry, DG; Cool, BL; Kifle, L; Lartey, K; Marsh, KC; Kempf-Grote, AJ; Kilgannon, P; Wisdom, W; Meyer, J; Gallatin, WM; Okasinski, GF Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression. J Med Chem44:988-1002 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vascular cell adhesion protein 1 |
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| Name: | Vascular cell adhesion protein 1 |
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| Synonyms: | CD106 antigen | INCAM-100 | VCAM-1 | VCAM1 | VCAM1_HUMAN | Vascular cell adhesion protein 1 | Vascular cell adhesion protein 1 (VCAM-1) | Vascular cell adhesion protein 1 precursor |
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| Type: | Other Protein Type |
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| Mol. Mass.: | 81259.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19320 |
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| Residue: | 739 |
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| Sequence: | MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWR
TQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPE
IHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEV
TFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGG
SVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKN
RKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVR
SEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSS
VTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKA
LVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFP
APKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTP
KDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQL
KDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFA
RKANMKGSYSLVEAQKSKV
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| BDBM50098517 |
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| n/a |
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| Name | BDBM50098517 |
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| Synonyms: | 4-(3,4-Dimethyl-phenylsulfanyl)-thieno[2,3-c]pyridine-2-carboxylic acid amide | CHEMBL267125 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2OS2 |
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| Mol. Mass. | 314.425 |
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| SMILES | Cc1ccc(Sc2cncc3sc(cc23)C(N)=O)cc1C |
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| Structure | 
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