| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
|---|
| Ligand | BDBM50098532 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2822 (CHEMBL621508) |
|---|
| Ki | 0.26±n/a nM |
|---|
| Citation |  Chambers, JJ; Kurrasch-Orbaugh, DM; Parker, MA; Nichols, DE Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT(2A/2C) receptor agonists. J Med Chem44:1003-10 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2C |
|---|
| Name: | 5-hydroxytryptamine receptor 2C |
|---|
| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 51935.10 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P08909 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
|
|
|
|---|
| BDBM50098532 |
|---|
| n/a |
|---|
| Name | BDBM50098532 |
|---|
| Synonyms: | 2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran-4-yl)-1-methyl-ethyl-ammonium; chloride | CHEMBL6710 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H17BrNO2 |
|---|
| Mol. Mass. | 299.183 |
|---|
| SMILES | C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 |
|---|
| Structure | 
|
|---|
Search and Browse
