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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 1 | ||
| Ligand | BDBM50098626 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_220711 (CHEMBL843656) | ||
| IC50 | 5.2±n/a nM | ||
| Citation |  Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Design, synthesis, and discovery of a novel CCR1 antagonist. J Med Chem44:1429-35 (2001) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 1 | |||
| Name: | C-C chemokine receptor type 1 | ||
| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41180.69 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P32246 | ||
| Residue: | 355 | ||
| Sequence: |
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| BDBM50098626 | |||
| n/a | |||
| Name | BDBM50098626 | ||
| Synonyms: | 1-Cyclooctylmethyl-1-ethyl-4-[(9H-xanthene-9-carbonyl)-amino]-piperidinium; iodide | CHEMBL280751 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H41N2O2 | ||
| Mol. Mass. | 461.6582 | ||
| SMILES | CC[N+]1(CC2CCCCCCC2)CCC(CC1)NC(=O)C1c2ccccc2Oc2ccccc12 |(2.19,-1.52,;3.28,-2.61,;3.28,-4.15,;4.63,-4.92,;6.19,-4.23,;5.59,-2.82,;6.19,-1.39,;7.61,-.8,;9.03,-1.39,;9.63,-2.8,;9.03,-4.23,;7.61,-4.82,;1.94,-3.4,;.62,-4.15,;.62,-5.69,;1.97,-6.46,;3.32,-5.69,;-.69,-6.48,;-2.01,-5.71,;-2.04,-4.17,;-3.36,-6.48,;-4.67,-5.71,;-4.67,-4.17,;-6.02,-3.4,;-7.37,-4.17,;-7.34,-5.72,;-6.02,-6.48,;-6.02,-8.02,;-4.71,-8.79,;-4.71,-10.31,;-3.39,-11.08,;-2.04,-10.33,;-2.04,-8.8,;-3.36,-8.02,)| | ||
| Structure | 
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