| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-K receptor |
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| Ligand | BDBM50099636 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_220885 (CHEMBL824640) |
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| Ki | 7±n/a nM |
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| Citation |  Blaney, FE; Raveglia, LF; Artico, M; Cavagnera, S; Dartois, C; Farina, C; Grugni, M; Gagliardi, S; Luttmann, MA; Martinelli, M; Nadler, GM; Parini, C; Petrillo, P; Sarau, HM; Scheideler, MA; Hay, DW; Giardina, GA Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity and selectivity in quinoline tachykinin receptor antagonists. J Med Chem44:1675-89 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-K receptor |
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| Name: | Neuromedin-K receptor |
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| Synonyms: | NK-3 receptor | NK-3R | NK3R | NK3R_HUMAN | NKR | Neurokinin 3 receptor | Neurokinin B receptor | Neurokinin-3 (NK-3) | Neuromedin-3 receptor (NK-3R) | Neuromedin-3 receptor (NK3) | Neuromedin-K receptor | Neuromedin-K receptor (NK-3 receptor) | Neuromedin-K receptor (NK3) | Neuromedin-K receptor(NK3R) | TAC3R | TACR3 | Tachykinin receptor 3 | Tachykinin receptor 3 (NK3) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52221.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29371 |
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| Residue: | 465 |
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| Sequence: | MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGL
PVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVT
NYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIA
VDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEG
PKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKM
MIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLN
KRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADT
TRSSRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS
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| BDBM50099636 |
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| n/a |
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| Name | BDBM50099636 |
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| Synonyms: | 2-Phenyl-3-piperidin-1-ylmethyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide | CHEMBL47275 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33N3O |
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| Mol. Mass. | 463.6132 |
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| SMILES | CC[C@H](NC(=O)c1c(CN2CCCCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 |
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| Structure | 
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