| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50099816 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_202070 (CHEMBL811340) |
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| Ki | 1.9±n/a nM |
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| Citation |  Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands. J Med Chem44:1815-26 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50099816 |
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| n/a |
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| Name | BDBM50099816 |
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| Synonyms: | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-piperidin-4-yl)-amide | CHEMBL53401 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33BrN2O2 |
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| Mol. Mass. | 485.456 |
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| SMILES | COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1C2CCCC1CCC2 |
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| Structure | 
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