Reaction Details | |||
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Target | D(3) dopamine receptor | ||
Ligand | BDBM50099805 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_62749 (CHEMBL674590) | ||
Ki | 2.6±n/a nM | ||
Citation | Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands. J Med Chem44:1815-26 (2001) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
D(3) dopamine receptor | |||
Name: | D(3) dopamine receptor | ||
Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 | ||
Type: | Protein | ||
Mol. Mass.: | 49540.58 | ||
Organism: | Rattus norvegicus (Rat) | ||
Description: | P19020 | ||
Residue: | 446 | ||
Sequence: |
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BDBM50099805 | |||
n/a | |||
Name | BDBM50099805 | ||
Synonyms: | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-2-ylmethyl)-amide | CHEMBL301929 | ||
Type | Small organic molecule | ||
Emp. Form. | C27H33BrN2O2 | ||
Mol. Mass. | 497.467 | ||
SMILES | COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |wU:29.31,wD:27.30,25.34,23.36,17.18,TLB:30:25:31:22.29.28,21:22:24:27.31.26,THB:28:29:24:27.31.26,28:27:24:22.29.30,(7.12,-5.88,;8.45,-6.65,;8.47,-8.19,;9.8,-8.96,;9.8,-10.5,;8.47,-11.27,;8.45,-12.81,;7.13,-10.5,;5.79,-11.27,;4.47,-10.5,;4.47,-8.96,;5.79,-8.19,;7.13,-8.96,;11.13,-8.19,;11.11,-6.65,;12.45,-8.96,;13.77,-8.16,;15.11,-8.93,;15.49,-10.44,;17.33,-10.44,;17.74,-8.96,;16.43,-8.19,;16.39,-6.65,;17.9,-6.23,;19.31,-6.78,;20.31,-5.53,;20.34,-3.99,;18.93,-3.41,;17.58,-3.89,;17.59,-5.37,;18.93,-5.85,;17.9,-4.63,)| | ||
Structure |