| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50099857 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154331 |
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| IC50 | >100000±n/a nM |
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| Citation |  Thorarensen, A; Deibel, MR; Rohrer, DC; Vosters, AF; Yem, AW; Marshall, VD; Lynn, JC; Bohanon, MJ; Tomich, PK; Zurenko, GE; Sweeney, MT; Jensen, RM; Nielsen, JW; Seest, EP; Dolak, LA Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition. Bioorg Med Chem Lett11:1355-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | DEF_STAAU | PDF | Peptide Deformylase | Polypeptide deformylase | def | def1 | pdf1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 20556.80 |
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| Organism: | Staphylococcus aureus (strain Mu50 / ATCC 700699) |
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| Description: | ChEMBL_459563 |
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| Residue: | 183 |
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| Sequence: | MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVG
LAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAG
LVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDA
VEV
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|
|
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| BDBM50099857 |
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| n/a |
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| Name | BDBM50099857 |
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| Synonyms: | ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsaeure | Acethydroxamsaure | Acetic acid, oxime | Acetylhydroxamic acid | Cetohyroxamic acid | Lithostat | Methylhydroxamic acid | N-Acetyl hydroxyacetamide | N-Acetylhydroxylamine | N-Hydroxyacetamide | acetohydroxamic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C2H5NO2 |
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| Mol. Mass. | 75.0666 |
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| SMILES | CC(=O)NO |
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| Structure | 
|
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