| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50099895 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_60982 |
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| Ki | 148±n/a nM |
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| Citation |  Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. Bioorg Med Chem Lett11:1375-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41307.65 |
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| Organism: | RAT |
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| Description: | DOPAMINE D4.4 0 RAT::P30729 |
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| Residue: | 387 |
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| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
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| BDBM50099895 |
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| n/a |
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| Name | BDBM50099895 |
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| Synonyms: | 3-(4-Biphenyl-4-yl-piperazin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine | CHEMBL287671 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N4 |
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| Mol. Mass. | 368.4742 |
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| SMILES | C(N1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1c[nH]c2ncccc12 |
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| Structure | 
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